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However, persistent neurohormonal signaling and increased wall stress leads to hypertrophy of surviving cardiomyocytes, dilation of the left ventricle, and deterioration of myocardial contractility and eventually these changes can progress to heart failure (HF) or death [ 5, 6 ].
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Normal (subpulmonary) right ventricular pressure also varies considerably with age, respiratory status, and heart rhythm, structure, and function. Peak systolic pressure is typically 20–30 mmHg. End-diastolic pressure is typically equal or just slightly less than the right atrial “a” wave at 3–6 mmHg (Fig. 23.2 ).
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