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al5 then published the simplified Gorlin formula, using the peak LV–peak aortic pressures (or mean). The Hakki valve area formula is as follows: AVAHakki orMVAHakki ¼CO/√peak peak(LV-Ao)ormean(mitral) gradient, where AVA ¼ aortic valve area, MVA ¼ mitral valve area, and Ao ¼ aortic (Figure 1B)
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Measurement of the transmitral gradient by cardiac catheterization is frequently made with a simultaneous pulmonary artery wedge pressure (PAWP) and left ventricular (LV) pressure. However, as a result of the delay in transmission of the change in pressure contour and a phase shift, the gradient using a pulmonary artery wedge pressure will .
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