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Left ventricular outflow tract obstruction (due to SAM) leads to the extension of the systolic ejection phase and a decrease in ejection volume. It can also lead to coaptation of mitral leaflets and, as a result, to significant mitral insufficiency, which further impairs cardiac output ( 3).
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An evaluation based on quantitative criteria is fundamental in establishing the diagnosis and assessing the severity of LV dyssynchrony. The evaluation usually begins with standard echocardiographic criteria and proceeds with more advanced measurements to establish the presence of dyssynchrony.
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